Research Articles
Nature's Molecular Masterpieces: The Double-Agent Diterpenoids Fighting Disease
Explore the fascinating world of naturally occurring diterpenoid dimers - complex molecular structures with remarkable medicinal properties against cancer and antibiotic-resistant bacteria.
The Digital Treasure Hunt for Nature's Miracles: A Cautionary Tale
How computers promised a new golden age of drug discovery, and why scientists had to go back to the lab.
Unlocking Nature's Hidden Medicine: Exploring Bacterial Diversity with BGC Atlas
Discover how BGC Atlas revolutionizes drug discovery by exploring bacterial chemical diversity through metagenomics and bioinformatics.
Combinatorial Chemistry: Accelerating Nature's Pharmacy into the Modern Age
Explore how combinatorial chemistry revolutionizes ethnopharmacology by combining traditional knowledge with modern drug discovery techniques.
Nature's Blueprint: The Molecular Secrets Hidden in Plants, Bugs, and Mold
Discover how natural product scaffolds from plants, marine creatures, and microorganisms are revolutionizing medicinal chemistry and drug discovery.
IMPDH: The Metabolic Gatekeeper Revolutionizing Drug Discovery
Explore how Inosine monophosphate dehydrogenase (IMPDH) is emerging as a crucial therapeutic target for cancer, infections, and other diseases through its role in GTP biosynthesis.
Molecular Masterpieces: The Artistic Synthesis of Nature's Complex Medicines
Explore the groundbreaking total synthesis of indotertine A and drimentines A, F, and G - a breakthrough in medicinal chemistry and drug discovery.
Reinvigorating Nature's Medicine Cabinet: How Synthetic Biology is Revolutionizing Drug Discovery
Explore how synthetic biology and combinatorial biosynthesis are transforming natural product discovery and drug development through innovative engineering approaches.
The Digital Treasure Hunt for Tomorrow's Medicines
How scientists are using genetic blueprints to uncover nature's hidden healing compounds through genome mining and biosynthesis research.
The Undruggables No More: How Science Is Hitting Medicine's Most Elusive Targets
Revolutionary strategies in drug discovery are targeting previously 'undruggable' proteins, transforming treatment options for cancer, neurology, and immunology.